One pill, twice-daily dosing fits into your patient’s lifestyle
Recommended dosage of ORLYNVAH is:
1 pill
Twice daily for 5 days
With or without food
Convenient treatment at home with a simple dosing schedule and low pill burden
Additional ORLYNVAH dosing considerations
If a dose is missed, instruct patients to take the next dose as soon as possible
Remind patients to not double the dose to make up for the missed dose
No dosage adjustment is required for ORLYNVAH in patients with creatinine clearance (CrCl) ≥15 mL/min
Not recommended in patients with CrCl less than 15 mL/min or on hemodialysis
Can be taken with or without food. However, ORLYNVAH is recommended to be taken with food. When taken with food, there is increased bioavailability (Cmax increased 45% and AUC increased 48%) and may lower incidence of diarrhea
Why ORLYNVAH?
Power of a penem in an oral formulation1
ORLYNVAH safety was evaluated in more than 1900 patients
The majority of adverse events were mild1-3