ORLYNVAH is designed for women who have limited or no alternative treatment options when treating uUTIs1
ORLYNVAH is for women with uncomplicated UTI who have:
A history of recurrence due to resistant pathogens and exposure to multiple antibiotic regimens2,3
A history of treatment failures3
Existence of risk factors that may lead to progression without effective treatment4-6
Age
Comorbid conditions
Allergies to antibiotics that limit treatment options
ORLYNVAH is for the treatment of uUTIs caused by E coli, K pneumoniae, or P mirabilis in adult women with limited or no alternative oral antibacterial options.
Limitations of Use: Not for complicated UTI or step-down treatment after IV antibacterials or complicated intra-abdominal infections or as step-down treatment after IV antibacterials.
A history of recurrence due to resistant pathogens and exposure to multiple antibiotic regimens2,3
A history of treatment failures
Existence of risk factors that may lead to progression without effective treatment4-6
Age
Comorbid conditions
Allergies to antibiotics that limit treatment options
ORLYNVAH is for the treatment of uUTIs caused by E coli, K pneumoniae, or P mirabilis in adult women with limited or no alternative oral antibacterial options.
Limitations of Use: Not for complicated UTI or step-down treatment after IV antibacterials or complicated intra-abdominal infections or as step-down treatment after IV antibacterials.
Consider ORLYNVAH for patients like these*
Chloe, 53
Married; marketing professional
uUTI diagnosis:
Urine white blood cell count ≥10 cells/HPF
Medical history:
Has experienced 3 UTIs in the past 6 months, with the most recent showing quinolone-resistant Escherichia coli
Previously treated with multiple courses of ciprofloxacin and trimethoprim/sulfamethoxazole
Culture results pending, but living in a region with high rates of multidrug-resistant organisms
Symptoms over 24 hours:
Pain and burning on urination
Urinary urgency and frequency
Comorbidities:
Depression treated with fluoxetine
Why ORLYNVAH:
Chloe needs a treatment for her recurrent, resistant uUTIs that doesn’t require IV therapy
HPF=high power field.
Sophia, 46
Single; teacher
uUTI diagnosis:
Acute bacterial cystitis, urinalysis positive for leukocyte esterase
Known antibiotic-resistant pathogen
Symptoms over 72 hours:
Urinary urgency
Pain and burning on urination
Comorbidities:
Type 2 diabetes that is being treated with metformin
Why ORLYNVAH:
Sophia is looking for a treatment for her uUTI so it doesn’t progress to a severe infection since she is immunosuppressed
Theresa, 66
Retired; 2 young grandchildren
uUTI diagnosis:
Symptoms consistent with uUTI
Symptoms over 48 hours:
Urinary frequency
Pain and burning on urination
Suprapubic pain
Comorbidities:
High blood pressure that is controlled with a beta-blocker and mild chronic kidney disease
Why ORLYNVAH:
Theresa is looking for a treatment that will not interfere with her daily medications and will not exacerbate her comorbidities
*Not actual patient profiles, for illustrative purposes only.
Convenient, at-home dosing
A one pill, twice-daily, 5-day oral treatment1
ORLYNVAH safety was evaluated in more than 1900 patients
The majority of adverse events were mild1,7,8